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Mitral annular calcification (MAC) is a multifactorial chronic degenerative process in which calcium with lipid is deposited in the annular fibrosa ring of the heart's mitral valve. MAC was first discovered and described in 1908 by M. Bonninger in the journal Deutsche Medizinische Wochenschrift . [ 1 ]
Secondary mitral regurgitation is due to the dilatation of the left ventricle that causes stretching of the mitral valve annulus and displacement of the papillary muscles. This dilatation of the left ventricle can be due to any cause of dilated cardiomyopathy including aortic insufficiency , nonischemic dilated cardiomyopathy , and ...
The mitral annulus is a fibrous ring that is attached to the mitral valve leaflets. Unlike prosthetic valves, it is not continuous. The mitral annulus is saddle shaped and changes in shape throughout the cardiac cycle. [10] The annulus contracts and reduces its surface area during systole to help provide complete closure of the leaflets.
Processes that lead to aortic insufficiency usually involve dilation of the valve annulus, thus displacing the valve leaflets, which are anchored in the annulus. [5] Mitral stenosis is caused largely by rheumatic heart disease, though is rarely the result of calcification. In some cases, vegetations form on the mitral leaflets as a result of ...
Mitral valve replacement is a procedure whereby the diseased mitral valve of a patient's heart is replaced by either a mechanical or tissue (bioprosthetic) valve. The mitral valve may need to be replaced because: [1] The valve is leaky (mitral valve regurgitation) The valve is narrowed and doesn't open properly (mitral valve stenosis) Causes of ...
When the left ventricle contracts during systole, a ton of pressure is generated so the blood can be pumped out the aortic valve, so a lot of pressure pushes on that closed mitral valve, but normally the papillary muscles and connective tissue called chordae tendineae, or heart strings, keep the valve from prolapsing or falling back into the ...
Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.
Mitral valve prolapse classification. Diagnosis of mitral valve prolapse is based on modern echocardiographic techniques which can pinpoint abnormal leaflet thickening and other related pathology. Echocardiography is the most useful method of diagnosing a prolapsed mitral valve. Two- and three-dimensional echocardiography is particularly ...
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