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Visual processing abnormalities in schizophrenia are commonly found, and contribute to poor social function. [ 1 ] There is evidence that schizophrenia affects perception of contrast and motion , control of eye movements , detection of visual contours, and recognition of faces or facial expressions .
The development of the hypothesis allowed for the integration of the GABAergic and oscillatory abnormalities into the converging disease model and made it possible to discover the causes of some disruptions. [2] Like the dopamine hypothesis, the development of the glutamate hypothesis developed from the observed effects of mind-altering drugs.
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
A Cochrane review found limited evidence for its possible antipsychotic effects in the treatment of schizophrenia and called for more studies. [164] Another review found limited evidence for its use as an add-on therapy for the relief of symptoms but positive results were found for the treatment of sleep disorders that often accompany ...
Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7]
The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine-receptor antagonistic effects. The ...
Primary process thinking, which is only encountered in dreams and in early childhood by modern man, is adapted by the schizophrenic to reduce destructive anxiety. Aristotelian logic is abandoned almost entirely, and primary process thinking gains more and more footing as the disease progresses from acute to chronic schizophrenia.
There is a great deal of evidence to show that schizophrenia is a heritable disease. It has been calculated that the heritability of schizophrenia is around 80%, and within that heritability 30% of the variability comes from single nucleotide polymorphisms and another 30% from large copy number variants (CNVs).