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The isthmus (also called the central pancreas) is the region of the gland that runs anterior to the superior mesenteric artery; by convention, it divides the right and left sides of the pancreas. [2] The ventral pancreatic bud forms the pancreatic head and uncinate process. The glands continue to develop but the duct systems anastomose.
Intraductal papillary mucinous neoplasm (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN tumors produce mucus, [1] and this mucus can form pancreatic cysts. [2] Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. [1]
Pancreatic cancer is among the most deadly forms of cancer globally, with one of the lowest survival rates. In 2015, pancreatic cancers of all types resulted in 411,600 deaths globally. [8] Pancreatic cancer is the fifth-most-common cause of death from cancer in the United Kingdom, [19] and the third most-common in the United States. [20]
The pancreatic duct is generally regarded as abnormally enlarged if being over 3 mm in the head and 2 mm in the body or tail on CT scan. [9] Pancreatic duct or parts of pancreatic duct can be demonstrated on ultrasound in 75 to 85% of people. [10] Pancreatic ductal carcinoma is a common form of pancreatic cancer.
Pancreatic development begins with the formation of a dorsal and ventral pancreatic bud. Each joins with the foregut through a duct. The dorsal pancreatic bud forms the neck, body, and tail of the developed pancreas, and the ventral pancreatic bud forms the head and uncinate process. [11]
A pancreatic tumor is an abnormal growth in the pancreas. [1] In adults, almost 90% are pancreatic cancer and a few are benign. [1] Pancreatic tumors are rare in children. [1] Classification is based on cellular differentiation (ductal, acinar, neuroendocrine, other) and gross appearance (intraductal, cystic, solid). [1]
Uncinate process of ethmoid bone, a process located in the nasal cavity; Uncinate process of vertebra, a hook-shaped process on the lateral borders (side edges) of the superior (top) surface of the vertebral bodies of the third to the seventh cervical vertebrae; Uncinate process of pancreas, a small projection from the pancreas
The first recorded case of pancreatic injury was published in The Lancet in 1827. [8] At the time, death as a result of injury was deemed to be "universal". [8] The first successful surgery to repair a transected pancreas was performed in 1904 by Garré, who reported the case the following year. [5] [9] [10]