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  2. Electrophilic aromatic directing groups - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_aromatic...

    An electron donating group (EDG) or electron releasing group (ERG, Z in structural formulas) is an atom or functional group that donates some of its electron density into a conjugated π system via resonance (mesomerism) or inductive effects (or induction)—called +M or +I effects, respectively—thus making the π system more nucleophilic.

  3. Captodative effect - Wikipedia

    en.wikipedia.org/wiki/Captodative_effect

    The captodative effect is the stabilization of radicals by a synergistic effect of an electron-withdrawing substituent and an electron-donating substituent. [2] [3] The name originates as the electron-withdrawing group (EWG) is sometimes called the "captor" group, whilst the electron-donating group (EDG) is the "dative" substituent. [3]

  4. Inductive effect - Wikipedia

    en.wikipedia.org/wiki/Inductive_effect

    In Organic chemistry, the inductive effect in a molecule is a local change in the electron density due to electron-withdrawing or electron-donating groups elsewhere in the molecule, resulting in a permanent dipole in a bond. [1] It is present in a σ (sigma) bond, unlike the electromeric effect which is present in a π (pi) bond.

  5. Mesomeric effect - Wikipedia

    en.wikipedia.org/wiki/Mesomeric_effect

    The +M effect, also known as the positive mesomeric effect, occurs when the substituent is an electron donating group. The group must have one of two things: a lone pair of electrons, or a negative charge. In the +M effect, the pi electrons are transferred from the group towards the conjugate system, increasing the density of the system.

  6. Electronic effect - Wikipedia

    en.wikipedia.org/wiki/Electronic_effect

    When this center is an electron rich carbanion or an alkoxide anion, the presence of the electron-withdrawing substituent has a stabilizing effect. Similarly, an electron-releasing group (ERG) or electron-donating group (EDG) releases electrons into a reaction center and as such stabilizes electron deficient carbocations .

  7. Electron-rich - Wikipedia

    en.wikipedia.org/wiki/Electron-rich

    Similarly, benzene derivatives with electron-donating groups (EDGs) are attacked by electrophiles faster than in benzene. [6] The electron-donating vs electron-withdrawing influence of various functional groups have been extensively parameterized in linear free energy relationships .

  8. Electron-withdrawing group - Wikipedia

    en.wikipedia.org/wiki/Electron-withdrawing_group

    An electron-withdrawing group (EWG) is a group or atom that has the ability to draw electron density toward itself and away from other adjacent atoms. [1] This electron density transfer is often achieved by resonance or inductive effects.

  9. Staudinger synthesis - Wikipedia

    en.wikipedia.org/wiki/Staudinger_synthesis

    Electron-donating groups on the imine facilitate this step, while electron-withdrawing groups impede the attack. [8] The second step is either an intramolecular nucleophilic ring closure or a conrotatory electrocyclic ring closure. [9] The second step is different from typical electrocyclic ring closures as predicted by the Woodward–Hoffmann ...