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  2. Receptor (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Receptor_(biochemistry)

    Receptors of a particular type are linked to specific cellular biochemical pathways that correspond to the signal. While numerous receptors are found in most cells, each receptor will only bind with ligands of a particular structure. This has been analogously compared to how locks will only accept specifically shaped keys. When a ligand binds ...

  3. Cell signaling - Wikipedia

    en.wikipedia.org/wiki/Cell_signaling

    Enzyme-linked receptors (or catalytic receptors) are transmembrane receptors that, upon activation by an extracellular ligand, causes enzymatic activity on the intracellular side. [33] Hence a catalytic receptor is an integral membrane protein possessing both enzymatic, catalytic, and receptor functions. [34]

  4. Cell surface receptor - Wikipedia

    en.wikipedia.org/wiki/Cell_surface_receptor

    Membrane receptors are mainly divided by structure and function into 3 classes: The ion channel linked receptor; The enzyme-linked receptor; and The G protein-coupled receptor. Ion channel linked receptors have ion channels for anions and cations, and constitute a large family of multipass transmembrane proteins.

  5. Hill equation (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Hill_equation_(biochemistry)

    In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration. A ligand is "a substance that forms a complex with a biomolecule to serve a biological purpose", and a macromolecule is a very large molecule, such as a ...

  6. JAK-STAT signaling pathway - Wikipedia

    en.wikipedia.org/wiki/JAK-STAT_signaling_pathway

    There are three key parts of JAK-STAT signalling: Janus kinases (JAKs), signal transducer and activator of transcription proteins (STATs), and receptors (which bind the chemical signals). [1] Disrupted JAK-STAT signalling may lead to a variety of diseases, such as skin conditions, cancers, and disorders affecting the immune system. [1]

  7. Scatchard equation - Wikipedia

    en.wikipedia.org/wiki/Scatchard_equation

    The Scatchard equation is an equation used in molecular biology to calculate the affinity and number of binding sites of a receptor for a ligand. [1] It is named after the American chemist George Scatchard.

  8. Protein–ligand complex - Wikipedia

    en.wikipedia.org/wiki/Protein–ligand_complex

    Crystal structure of W741L mutant androgen receptor ligand-binding domain and ()-bicalutamide complex. [1] An example of a protein–ligand complex. A protein–ligand complex is a complex of a protein bound with a ligand [2] that is formed following molecular recognition between proteins that interact with each other or with other molecules.

  9. Mannose 6-phosphate receptor - Wikipedia

    en.wikipedia.org/wiki/Mannose_6-phosphate_receptor

    [2] [3] The larger receptor is known as the cation-independent mannose 6-phosphate receptor , while the smaller receptor requires divalent cations to efficiently recognize lysosomal hydrolases. [3] While divalent cations are not essential for ligand binding by the human CD-MPR, the nomenclature has been retained.

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    related to: biochemistry of receptors and functions notes 6th version key of math