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By selectively targeting caPCNA, it may be possible to kill cancer cells without affecting healthy tissues. [5] In vitro testing demonstrated that AOH1996 inhibited the growth and induced cell cycle arrest and apoptotic cell death in a wide variety of cancer cell lines, but had no effect on several normal, nonmalignant cell types.
Bioluminescent activated destruction or BLADe refers to a technique used to kill cancer cells. [1] [unreliable medical source?It works by first altering the cells in an organism, once they become cancerous, to create the firefly light source luciferin and luciferase to create light.
Chemotherapy can boost tumor immunity in two main ways: (a) by killing cancer cells through immunogenic cell death, and (b) by affecting both cancerous and normal cells in the tumor environment. Despite this, many chemotherapy treatments can also suppress the immune system by causing lymphopenia or impairing lymphocyte function.
A professor with the University of Texas at San Antonio has created a new method to kill cancer cells that are traditionally difficult to eradicate.
The resulting decay reaction yields high-energy alpha particles that kill the cancer cells that have taken up enough 10 B. All clinical experience with NCT to date is with boron-10; hence this method is known as boron neutron capture therapy (BNCT). [1]
Conventional photodynamic therapy (PDT) uses a non-specific photosensitizer which can be activated by a non-ionizing light to kill cancer cells. Photosensitizers [broken anchor] are molecules that rapidly destroy cells though the production of reactive oxygen species (ROS) when exposed to light at specific wavelength. [5]
Despite the promises of early in vivo lab work, these viruses do not specifically infect cancer cells, but they still kill cancer cells preferentially. [38] While overall survival rates are not known, short-term response rates are approximately doubled for H101 plus chemotherapy when compared to chemotherapy alone. [38]
Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...
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