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Metformin is one of many medications that can cause lactic acidosis. Symptoms of lactic acidosis include nausea, vomiting and weakness. Fortunately, the risk of lactic acidosis is a rare side ...
10. You're taking medications that cause weight gain "Certain medications can induce weight gain or hinder weight loss by altering hormones, changing appetite, or causing water retention," says Costa.
People on sulfonylureas, for example, may need to take a lower dose if they take metformin as the combo can increase the risk of hypoglycemia (low blood sugar). KucherAV/istockphoto
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Usually, people are recommended to control diet, exercise, and maintain a healthy weight, although some people may need medications to control their blood sugar levels. Other goals of diabetes management are to prevent or treat complications that can result from the disease itself and from its treatment.
Metformin is approved for prediabetes and type 2 diabetes and has become one of the more commonly prescribed medications for insulin resistance. [ 60 ] The Diabetes Prevention Program (DPP) showed that exercise and diet were nearly twice as effective as metformin at reducing the risk of progressing to type 2 diabetes. [ 61 ]
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia. This can be a medication or a naturally occurring neuropeptide hormone, such as ghrelin , orexin or neuropeptide Y , [ 1 ] [ 2 ] which increases hunger and therefore enhances food consumption .