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Raloxifene, sold under the brand name Evista among others, is a medication used to prevent and treat osteoporosis in postmenopausal women and those on glucocorticoids. [6] For osteoporosis it is less preferred than bisphosphonates. [6] It is also used to reduce the risk of breast cancer in those at high risk. [6] It is taken by mouth. [6]
Estradiol/raloxifene (E2/RLX) is a tissue-selective estrogen complex (TSEC) which was studied for potential use in menopausal hormone therapy but was never marketed. [ 2 ] [ 1 ] [ 3 ] [ 4 ] [ 5 ] Today, E2/RLX is not generally used due to concerns of endometrial hyperplasia .
Raloxifene belongs to the second-generation benzothiophene SERM drugs. It has a high affinity for the ER with potent antiestrogenic activity and tissue-specific effects distinct from estradiol. [19] Raloxifene is an ER agonist in bone and the cardiovascular system, but in breast tissue and the endometrium it acts as an ER antagonist.
Blood doping is the injection of red blood cells, related blood products that contain red blood cells, or artificial oxygen containers. This is done by extracting and storing one's own blood prior to an athletic competition, well in advance of the competition so that the body can replenish its natural levels of red blood cells, and subsequently injecting the stored blood immediately before ...
There are a few foods you may want to skip on Thanksgiving if you're taking a GLP-1 medication such as Ozempic, dietician Kylie Bensley, founder of the women’s nutrition company, Sulinu, tells ...
Ospemifene might not have an adverse influence on coagulation, in contrast to estrogens and other SERMs like tamoxifen and raloxifene. [9] A binding assay was also performed to measure the affinity of ospemifene for the estrogen receptor (ERα and ERβ). [10] The study showed that ospemifene bound ERα and ERβ with similar affinity. [10]
Magnesium is important to the health of your bones, heart and brain. It's great to get it via food, but here's the best time to take magnesium supplements.
The minimum amount of cardio exercise you can get away with each week depends on your resting heart rate and your specific fitness goals, according to trainers.
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