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The tunica intima (Neo-Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells (and macrophages in areas of disturbed blood flow), [1] [2] and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.
The structure of the vasa vasorum varies with the size, function and location of the vessels. Cells need to be within a few cell-widths of a capillary to stay alive. In the largest vessels, the vasa vasorum penetrates the outer (tunica adventitia) layer and middle (tunica media) layer almost to the inner (tunica intima) layer.
Vein stripping is a surgical procedure done under general or local anaesthetic to aid in the treatment of varicose veins and other manifestations of chronic venous disease. The vein "stripped" (pulled out from under the skin using minimal incisions) is usually the great saphenous vein. The surgery involves making incisions (usually the groin ...
Tunica albuginea (disambiguation), three different layers of connective tissue; Tunica vasculosa (disambiguation), two different vascular layers; Tunica externa, outermost tunica (layer) of a blood vessel, surrounding the tunica media; Tunica intima, for short, is the innermost tunica (layer) of an artery or vein
Coronary artery bypass graft surgery has been in practice since the 1960s. Historically, vessels—such as the great saphenous vein in the leg or the radial artery in the arm—were obtained using a traditional "open" procedure that required a single, long incision from groin to ankle, or a "bridging" technique that used three or four smaller incisions.
The first uses a cardiopulmonary bypass machine, a machine which takes over the functions of the heart and lungs during surgery by circulating blood and oxygen. With the heart in cardioplegic arrest, harvested arteries and veins are used to connect across problematic regions—a construction known as surgical anastomosis.
A synthetic graft remains open in 33 to 50 out of 100 people 5 years after Popliteal bypass surgery was carried out, whereas using veins, the bypass remains unobstructed in 66 out of 100 people. [12] Moreover, the particular vein, great saphenous vein was shown to be more durable over the years after surgery. [5]
Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins, a treatable condition. [2]