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Vickers is known for his research into prostate cancer screening. [6] In 2011, he published a study which found that PSA velocity—the change in the blood level of prostate-specific antigen (PSA)--was not a more accurate predictor of prostate cancer than comparing PSA levels to a specific threshold. [7]
If the examination suggests anomalies, a PSA test is performed. If an elevated PSA level is found, a follow-up test is then performed. [2] A 2018 review recommended against primary care screening for prostate cancer with DRE due to the lack of evidence of the effectiveness of the practice. [23]
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
Here’s an overview of what PSA test results mean and the next steps if your levels are high. What Your PSA Test Results Mean. THE PSA IS a good initial “check engine light” for the prostate, ...
PSA levels between 4 and 10 suggest you could have about a 25 percent chance of prostate cancer, and levels over 10 signal that your chance of having the cancer is more than 50 percent.
Men with high PSA levels are often recommended to repeat the blood test four to six weeks later, as PSA levels can fluctuate unrelated to prostate cancer. [17] Benign prostatic hyperplasia, prostate infection, recent ejaculation, and some urological procedures can increase PSA levels; taking 5α-reductase inhibitors can decrease PSA levels. [15]
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A look back at how "48 Hours" covered the 1996 Christmastime murder of JonBenét Ramsey in 2002, and what her father John Ramsey says about the unsolved Colorado case nearly 28 years later.