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Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. [17] Medically, it is an anticonvulsant used to treat multiple forms of epilepsy. [4]
CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]
Managing the pain and stiffness of arthritis can be a challenge, so many people are turning to cannabidiol (CBD) for relief. In a poll conducted by the Arthritis Foundation, 29 percent of ...
Myalgia or muscle pain is a painful sensation evolving from muscle tissue.It is a symptom of many diseases.The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, especially when there has been no injury.
Does CBD work? The medication Epidiolex — the only CBD-based treatment approved by the U.S. Food and Drug Administration (FDA) — has been proven effective for severe seizure disorders. A twice ...
The scientific evidence for CBD and arthritis is still gathering. Twenty-nine percent of people who responded to an Arthritis Foundation poll said that they currently use CBD to manage pain ...
The act established the position of Associate Director for arthritis and related musculoskeletal diseases and authorized an interagency arthritis coordinating committee; community demonstration project grants; an arthritis data bank; an information clearinghouse; and comprehensive centers for research, diagnosis, treatment, rehabilitation and ...
This makes it a good choice if you have the painful and inflamed joints associated with arthritis. The CBD oil is available in regular strength (500mg), extra strength (1000mg), maximum strength ...