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Peripherally selective trans-3,4-dimethyl-4-(3-hydroxylphenyl)piperidine opioid antagonists were developed for the treatment of gastrointestinal motility disorder by Zimmerman and his coworkers. From that, they derived the 4-(3-hydroxyphenyl)-3,4-dimethylpiperidine scaffold with functional groups spanning various sizes, charge, and polarity to ...
Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating diarrhea symptoms and improving stool consistency and frequency. [4] Unlike other opiates, loperamide does not cross the blood brain barrier, so there is minimal risk for abuse. [5]
Smart pill may refer to: Capsule endoscopy, use of a pill containing a small camera used to record internal images of the gastrointestinal tract for use in medical diagnosis; Digital pill, a pill which contains a drug and an ingestible sensor that transmits medical data; Colloquial term for purported nootropic agents
Semaglutide upset stomach symptoms, including nausea, aren’t forever. Try tweaking what and how you eat to minimize nausea. Avoiding high-fat foods, large meals, and liquids during mealtimes may ...
Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions. [4] It is a combined D 2 receptor antagonist and acetylcholinesterase inhibitor . [ 5 ] [ 6 ] Itopride is the dimethoxy analog of trimethobenzamide .
Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT 4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system.
A prokinetic agent (also prokineticin, gastroprokinetic agent, gastrokinetic agent or propulsive) is a type of drug which enhances gastrointestinal motility by increasing the frequency or strength of contractions, but without disrupting their rhythm. [1]
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