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Clonidine, sold under the brand name Catapres among others, is an α 2A-adrenergic receptor agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (e.g., alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]
Clonidine was initially developed as a treatment for high blood pressure. Low doses in evenings and/or afternoons are sometimes used in conjunction with stimulants to help with sleep and because clonidine sometimes helps moderate impulsive and oppositional behavior and may reduce tics. [96] It may be more useful for comorbid Tourette syndrome.
Clonidine and other imidazoline compounds have also been shown to reduce muscle spasms by their central nervous system activity. Tizanidine is perhaps the most thoroughly studied clonidine analog, and is an agonist at α 2-adrenergic receptors, but reduces spasticity at doses that result in significantly less hypotension than clonidine. [26]
at bedtime or half strength quaque hora somni ii two tablets duos doses iii three tablets trēs doses n.p.o., npo, NPO nothing by mouth / not by oral administration: nil per os o.d., od, OD right eye. once a day (United Kingdom) oculus dexter omne in die o.s., os, OS left eye: oculus sinister o.u., ou, OU both eyes: oculus uterque p.c. after ...
But I still doubt that Clonidine, by itself, is an appropriate treatment for either disorder. 70.90.220.214 22:04, 27 March 2007 (UTC) There is a lot of info on this page[] --Clawed 05:07, 16 Jul 2004 (UTC) Unless I got the wrong drug, Clonidine is also used off-label to treat insomnia. I once took it when I was young in really small doses.
The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker ...
The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence. The complete list of Schedule II substances is as follows.
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
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