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Clonidine may be used to ease drug withdrawal symptoms associated with abruptly stopping the long-term use of opioids, alcohol, benzodiazepines, and nicotine. [36] It can alleviate opioid withdrawal symptoms by reducing the sympathetic nervous system response such as tachycardia and hypertension , hyperhidrosis (excessive sweating), hot and ...
Clonidine was initially developed as a treatment for high blood pressure. Low doses in evenings and/or afternoons are sometimes used in conjunction with stimulants to help with sleep and because clonidine sometimes helps moderate impulsive and oppositional behavior and may reduce tics. [96] It may be more useful for comorbid Tourette syndrome.
Clonidine and other imidazoline compounds have also been shown to reduce muscle spasms by their central nervous system activity. Tizanidine is perhaps the most thoroughly studied clonidine analog, and is an agonist at α 2-adrenergic receptors, but reduces spasticity at doses that result in significantly less hypotension than clonidine. [26]
at bedtime hor. intermed. horis intermediis: at intermediate hours hor. tert. horis tertiis: every third hour h.s. hora somni (at the hour of sleep) at bedtime [or] half-strength ambiguous (2 meanings, easily conflated); spell out IBW ideal body weight (for dosing based on clearance estimation) ID intradermal IJ, inj. injectio: injection
every bedtime (from Latin quaque hora somni) q.i.d. four times each day (from Latin quater in die) (not deprecated, but consider using "four times a day" instead. See the do-not-use list) QIDS: Quick Inventory of Depressive Symptoms: q.l. as much as you like (from Latin quantum libet) q.m.t. also qm: every month q.n. every night QNS q.n.s.
But I still doubt that Clonidine, by itself, is an appropriate treatment for either disorder. 70.90.220.214 22:04, 27 March 2007 (UTC) There is a lot of info on this page[] --Clawed 05:07, 16 Jul 2004 (UTC) Unless I got the wrong drug, Clonidine is also used off-label to treat insomnia. I once took it when I was young in really small doses.
SNRIs are delivered orally, usually in the form of capsules or tablets. It is recommended to take SNRIs in the morning with breakfast, which does not affect drug levels, but may help with certain side effects. [48] Norepinephrine has activating effects in the body and therefore can cause insomnia in some patients if taken at bedtime. [49]
A systematic review and meta-analysis of 17 different studies found that taking a warm bath or shower 1–2 hours before bedtime for as little as 10 minutes shortens the sleep onset time and improves sleep efficiency and subjective sleep quality and increases the amount of deep sleep.
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