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Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (renal calculus) develops in the urinary tract. [2] Renal calculi typically form in the kidney and leave the body in the urine stream. [2] A small calculus may pass without causing symptoms. [2]
A kidney stone is a hard object, which can be as small as a grain of salt or as big as a golf ball, made from chemicals—calcium oxalate, uric acid, struvite, and cystine—found in our urine ...
Struvite kidney stones are also known as triple phosphate stones (calcium magnesium ammonium phosphate), owing to the presence of carbonate apatite that precipitates to accompany struvite at high pH. [10] [11] [12] Struvite and carbonate apatite precipitate in alkaline urine, forming kidney stones.
A number of important medical conditions are caused by stones: [citation needed] Nephrolithiasis (kidney stones) Can cause hydronephrosis (swollen kidneys) and kidney failure; Can predispose to pyelonephritis (kidney infections) Can progress to urolithiasis; Urolithiasis (urinary bladder stones) Can progress to bladder outlet obstruction
About 76% of kidney stones are partially or entirely of the calcium oxalate type. [6] They form when urine is persistently saturated with calcium and oxalate. Between 1% and 15% of people globally are affected by kidney stones at some point. [14] [15] In 2015, they caused about 16,000 deaths worldwide. [16]
The experimental thulium fiber laser (TFL) is being studied as a potential alternative to the holmium:YAG (Ho:YAG) laser for the treatment of kidney stones. The TFL has several potential advantages compared to Ho:YAG laser for lithotripsy, including a four times lower ablation threshold, a near single-mode beam profile, and higher pulse rates ...
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