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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Vomiting is a common condition affecting about 50% of pregnant women, with another 25% having nausea. [53] However, the incidence of HG is only 0.3–1.5%. [ 4 ] After preterm labor, hyperemesis gravidarum is the second most common reason for hospital admission during the first half of pregnancy. [ 16 ]
Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
For women that do not improve with initial treatment, medications, such as pyridoxine and doxylamine, may also be used. [9] A rare form of severe nausea and vomiting known as hyperemesis gravidarum can occur in 1% of pregnant women and can affect fetal and maternal health. [10]
Morning sickness, also called nausea and vomiting of pregnancy (NVP), is a symptom of pregnancy that involves nausea or vomiting. [1] Despite the name, nausea or vomiting can occur at any time during the day. [2] Typically the symptoms occur between the 4th and 16th weeks of pregnancy. [2]
The NFL playoffs begin with a six-game wild card weekend slate. The second game of the round features a divisional contest in the AFC bracket between the No. 3 seed Baltimore Ravens and the No. 6 ...
This 41% spike is credited by denomination leaders in a September 2023 report as the fruits of conservative disenfranchisement with mainstream evangelical groups, starting with COVID-19 and CREC ...
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
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