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Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]
Wernicke-Korsakoff syndrome (WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome (AKS [clarification needed]). Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome.
Up to 80% of WE patients who misuse alcohol develop Korsakoff's syndrome. [39] In Korsakoff's, is usually observed atrophy of the thalamus and the mammillary bodies, and frontal lobe involvement. [39] In a study, half of Wernicke–Korsakoff cases had good recovery from the amnesic state, which may take from 2 months to 10 years. [2]
UN: Estimate of life expectancy for various ages in 2023; Locations Life expectancy for population in general Life expectancy for male Life expectancy for female Sex gap; at birth bonus 0→15 at 15 bonus 15→65 at 65 bonus 65→80 at 80 at birth at 15 at 65 at 80 at birth at 15 at 65 at 80 at birth at 15 at 65 at 80 Hong Kong: 85.51: 0.21: 70 ...
A female baby born in Nagpur, India in June 2016 died after two days. She was the first case of harlequin ichthyosis reported in India. [39] [40] [41] Hannah Betts was born with the condition in 1989 in Great Britain, and died in 2022 at 32 years old. [42] Ng Poh Peng was born in 1991 in Singapore. Doctors had not expected her to live past her ...
Werner syndrome patients exhibit growth retardation, short stature, premature graying of hair, alopecia (hair loss), wrinkling, prematurely aged faces with beaked noses, skin atrophy (wasting away) with scleroderma-like lesions, lipodystrophy (loss of fat tissues), abnormal fat deposition leading to thin legs and arms, and severe ulcerations around the Achilles tendon and malleoli (around ankles).
In Russia, however, the sex-associated gap has been increasing as male life expectancy declines. [126] The longer average life span of females can lead to skewed statistical results in regard to sex differences. For example, females are often seen to be at a higher risk of bone fracture due to osteoporosis.
A–T can cause features of early aging such as premature graying of the hair. It can also cause vitiligo (an auto-immune disease causing loss of skin pigment resulting in a blotchy "bleach-splashed" look), and warts which can be extensive and recalcitrant to treatment. A small number of people develop a chronic inflammatory skin disease ...