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Trazodone, sold under many brand names, [1] is an antidepressant medication, [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
The drug is a silent antagonist of the serotonin 5-HT 1B receptor, unlike the related agent GR-127935. [ 1 ] [ 4 ] GR-55562 has around 10-fold selectivity for the serotonin 5-HT 1B receptor over the serotonin 5-HT 1D receptor and has only weak affinity for a number of other serotonin receptors .
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
It is both a precursor in the synthesis of aripiprazole and one of its metabolites. [ 1 ] [ 2 ] It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine ( m CPP), though it has been shown to act as a partial agonist of the dopamine D 2 and D 3 receptors.
These drugs act as antagonists or inverse agonists of the 5-HT 2A, α 1-adrenergic, and H 1 receptors, as partial agonists of the 5-HT 1A receptor, [3] and as inhibitors of the transporters. mCPP is an antagonist of the 5-HT 2B receptor, an agonist of the 5-HT 1A, [3] 5-HT 2C, and 5-HT 3 receptors, [4] [5] and acts as a partial agonist of the ...
These are the only minoxidil dosages approved by the FDA (U.S. Food and Drug Administration). At 2% and 5%, minoxidil is FDA-approved to treat androgenic alopecia ( male pattern baldness and ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
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related to: trazodone metabolites trazodonenui tablets uses 20 of 5goodrx.com has been visited by 100K+ users in the past month
109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Ranked at No. 20 on the 2020 Disruptor 50 list. - CNBC