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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Alcohol: Benzodiazepine: Time flip Time flipping Alcohol: Caffeine: Caffeinated alcoholic drink: Alcohol: Cannabis: Tincture of cannabis. Herb and Al. Judgement Day Cross fading, twisting, getting twisted [13] Called Judgement Day in Ghana when cannabis is added to the drink Alcohol: Cocaine: Snow-cone Snow-coning Ethanol is metabolized into ...

  3. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Benzodiazepines can cause death when mixed with other CNS depressants such as opioids, alcohol, or barbiturates. [7] [8] [9] GHB combined with alcohol can lead to a long-lasting coma-like state (‘G-sleep’) or even accidental death, particularly in light of GHB's narrow threshold for overdose. Depressants combined with stimulants. For example:

  4. Cross-tolerance - Wikipedia

    en.wikipedia.org/wiki/Cross-tolerance

    Benzodiazepine binding increases the binding of GABA and barbiturates maximize the time the pore is open. Both of these mechanisms allow for influx of chloride ions. When these drugs are taken together, especially with ethanol (drinking alcohol), there is a disproportionate increase in toxicity because the effects of both occur simultaneously ...

  5. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. [ 9 ] [ 10 ] A 2005 medical review advised patients to avoid all citrus juices until further research clarifies the risks. [ 11 ]

  6. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    Interactions may occur by simultaneous targeting of receptors, directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can lead to loss of consciousness. When two drugs affect each other, it is a drug–drug interaction (DDI ...

  7. Cialis and Alcohol: Is it Safe?

    www.aol.com/cialis-alcohol-safe-115800912.html

    Cialis and Alcohol Side Effects. When used as directed, Cialis may help treat dysfunction and boost satisfaction. More than 80 percent of men have satisfactory arousals after taking it.. But like ...

  8. What Happens When You Take Viagra While Drinking Alcohol?

    www.aol.com/lifestyle/happens-viagra-while...

    Alcohol and Viagra Interactions: Grapefruit Juice. While it’s generally alright to drink a small amount of alcohol with Viagra, you may need to be extra cautious if you like drinks containing ...

  9. Butalbital - Wikipedia

    en.wikipedia.org/wiki/Butalbital

    Mixing with alcohol, benzodiazepines, and other CNS-depressants increases the risk of intoxication, increases respiratory depression, and increases liver toxicity when in combination with paracetamol (acetaminophen). Use of butalbital and alcohol, benzodiazepines, and other CNS-depressants can contribute to coma, and in extreme cases, fatality.