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  2. Duchenne muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Duchenne_muscular_dystrophy

    Duchenne muscular dystrophy is the most common type of muscular dystrophy, [3] with a median life expectancy of 27–31 years. [5] [11] However, with comprehensive care, some individuals may live into their 30s or 40s. [3] Duchenne muscular dystrophy is considerably rarer in females, occurring in approximately one in 50,000,000 live female ...

  3. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    Many affected people will eventually become unable to walk [2] and Duchenne muscular dystrophy in particular is associated with shortened life expectancy. Muscular dystrophy was first described in the 1830s by Charles Bell. [2] The word "dystrophy" comes from the Greek dys, meaning "no, un-" and troph-meaning "nourish". [2]

  4. Gowers's sign - Wikipedia

    en.wikipedia.org/wiki/Gowers's_sign

    Gowers's sign is classically seen in Duchenne muscular dystrophy where it is mostly evident at 4–6 years, but also presents itself in centronuclear myopathy, myotonic dystrophy and various other conditions associated with proximal muscle weakness, including Becker muscular dystrophy, dermatomyositis and Pompe disease. For this maneuver, the ...

  5. List of neuromuscular disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_neuromuscular...

    Distal muscular dystrophy, also called distal myopathy, is essentially any muscle disease that preferentially affects the hands and/or feet, a much less common pattern than proximal muscle weakness. Late adult-onset type 1; Late adult-onset type 2a; Late adult-onset type 2b; Early adult-onset type 1; Early adult-onset type 2; Early adult-onset ...

  6. Pfizer reports patient death in Duchenne gene therapy study - AOL

    www.aol.com/news/pfizer-reports-patient-death...

    (Reuters) -A young patient died due to cardiac arrest after receiving Pfizer's experimental gene therapy being tested in a mid-stage trial for a muscle-wasting disorder called Duchenne muscular ...

  7. Physical therapy for Duchenne muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Physical_therapy_for...

    Devices to help a person with duchenne muscular dystrophy stand are a common treatment approach. [3] Orthotic devices are used (as discussed above) and also specific standing devices such as standing frames, standing wheelchairs, and tables that have a tilt function.

  8. Dystrophin-associated protein complex - Wikipedia

    en.wikipedia.org/wiki/Dystrophin-associated...

    Many forms of muscular dystrophy are associated with disorders of the dystrophin-associated protein complex. [6] Muscular dystrophy, the result of mutations in the genes that encode for dystrophin and the associated proteins that binds to it can arise in various forms. [7] The most common form is known as Duchenne muscular dystrophy (DMD). [8]

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