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[2] [3] They emphasize deprescribing medications that are unnecessary, which helps to reduce the problems of polypharmacy, drug interactions, and adverse drug reactions, thereby improving the risk–benefit ratio of medication regimens in at-risk people. [4] The criteria are used in geriatrics clinical care to monitor and improve the quality of ...
Kidney function gradually decreases as someone ages. The elderly are also likely to be underweight. In addition, these older people tend to be dehydrated and be taking other medications. These factors increase the likelihood of developing side effects of digoxin and digoxin toxicity. Often lowering the dose is considered by the prescriber. [6]
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
An FDA database that collects reports of adverse drug reactions from doctors and others shows 23 deaths of patients taking Leqembi. Holman at Eisai said it would be incorrect to assume the deaths ...
RSV vaccine side effects in older adults . The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache ...
Significant toxicity from benzodiazepines can occur in the elderly as a result of long-term use. [112] Benzodiazepines, along with antihypertensives and drugs affecting the cholinergic system, are the most common cause of drug-induced dementia affecting over 10 percent of patients attending memory clinics.
Less common adverse effects include vomiting, anxiety, hypertonia, cystitis, and increased libido. [20] [27] Like many other NMDA receptor antagonists, memantine behaves as a dissociative anesthetic at supratherapeutic doses. [28] Despite isolated reports, recreational use of memantine is rare due to the drug's long duration and limited ...
Concerns about polypharmacy include increased adverse drug reactions, drug interactions, prescribing cascade, and higher costs. [19] A prescribing cascade occurs when a person is prescribed a drug and experiences an adverse drug effect that is misinterpreted as a new medical condition, so the patient is prescribed another drug. [20]