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  2. Covert medication - Wikipedia

    en.wikipedia.org/wiki/Covert_medication

    Nursing guidelines in the New Zealand state the overriding a patient's wishes to not receive medication if the healthcare worker perceives it to be in the patient's best interest. [ 4 ] : 3 In the United Kingdom, only patients who have been deemed to lack mental capacity can be covertly medicated; capacity may be assessed by the prescriber of ...

  3. γ-Hydroxybutyric acid - Wikipedia

    en.wikipedia.org/wiki/Γ-hydroxybutyric_acid

    γ-Hydroxybutyric acid, also known as gamma-hydroxybutyric acid, GHB, or 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a depressant drug.It is a precursor to GABA, glutamate, and glycine in certain brain areas.

  4. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    Drug administration via the nasal cavity yields rapid drug absorption and therapeutic effects. [33] This is because drug absorption through the nasal passages does not go through the gut before entering capillaries situated at tissue cells and then systemic circulation and such absorption route allows transport of drugs into the central nervous ...

  5. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    Interactions with other drugs (e.g., antacids, alcohol, nicotine) Interactions with other foods (e.g., grapefruit juice, pomello, cranberry juice, brassica vegetables) Transporters: Substrate of efflux transporters (e.g. P-glycoprotein) Health of the gastrointestinal tract; Enzyme induction/inhibition by other drugs/foods:

  6. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

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  8. Medication - Wikipedia

    en.wikipedia.org/wiki/Medication

    A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. [ 1 ] [ 2 ] Drug therapy ( pharmacotherapy ) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for ...

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