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Vortioxetine was under development for the treatment of generalized anxiety disorder [59] and attention-deficit hyperactivity disorder (ADHD) [60] but development for these indications was discontinued. [61] As of August 2021, vortioxetine remains in development for the treatment of anxiety disorders, binge-eating disorder, and bipolar disorder ...
This is a list of investigational social anxiety disorder drugs, or drugs that are currently under development for clinical use in the treatment of social anxiety disorder (SAD; or social phobia) but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
MDMA (Midomafetamine, 3,4-methylenedioxymethamphetamine, "ecstasy") – serotonin–norepinephrine–dopamine releasing agent and 5-HT 1 and 5-HT 2 receptor agonist – specifically under development as an aid to psychotherapy for post-traumatic stress disorder [14] [15] [16]
Vorapaxar is an antiplatelet drug of the PAR-1 antagonist family. It functions by inhibiting thrombin-related platelet aggregation.This mechanism works by a different pathway from other antiplatelet medications, such as aspirin and P2Y12 inhibitors.
The second generation thienopyridine P2Y 12 receptor blocker clopidogrel is an effective antiplatelet agent useful for treatment of ischemic cerebrovascular, cardiac and peripheral arterial release. [27] Like other thienopyridine drugs, the drug was often combined with aspirin in clinical use. [23]
Sarpogrelate (former developmental code names MCI-9042, LS-187,118) is a drug which acts as an antagonist at the serotonin 5-HT 2A [1] [2] 5-HT 2B, and 5-HT 2C receptors. [3] [4] However, its affinities for the human 5-HT 2C and 5-HT 2B receptors are about one and two orders of magnitude lower than for the human 5-HT 2A receptor, respectively. [3]
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