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Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
The test is used in the differential diagnosis of secondary and tertiary hypothyroidism. First, blood is drawn and a baseline TSH level is measured. Then, TRH is administered via a vein. After 30 minutes blood is drawn again and the levels of TSH are measured and compared to the baseline. Some authors recommend additional blood sampling at 15 ...
Reader's DigestSilent Signs of a Thyroid ProblemKnow the symptoms of an overactive and underactive thyroid before it interferes with your life. Several mysterious symptoms—from weight changes to ...
Augmented calcium levels in the blood (by as much as 25% – known as hypercalcaemia). This can cause stomach upset, excessive urination, and impaired kidney function. [13] Diabetes may be activated or intensified, and its control worsened. The diabetes is ameliorated or may disappear when the thyrotoxicosis is treated. [4]
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these. [44]
Estradiol disrupts thyroid hormone production because high blood levels of estrogen signal the liver to increase the production of thyroid-binding globulin (TBG). This is an inhibitor protein that binds to the thyroid hormone, reducing the amount of T 3 and T 4 available for use by cells. [37]
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