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The respiratory quotient value indicates which macronutrients are being metabolized, as different energy pathways are used for fats, carbohydrates, and proteins. [1] If metabolism consists solely of lipids, the respiratory quotient is approximately 0.7, for proteins it is approximately 0.8, and for carbohydrates it is 1.0.
Studies of energy metabolism using both methods provide convincing evidence for the validity of the respiratory quotient (RQ), which measures the inherent composition and utilization of carbohydrates, fats and proteins as they are converted to energy substrate units that can be used by the body as energy.
where RQ is the respiratory quotient (ratio of volume CO 2 produced to volume of O 2 consumed), is 21.13 kilojoules (5.05 kcal), the heat released per litre of oxygen by the oxidation of carbohydrate, and is 19.62 kilojoules (4.69 kcal), the value for fat. This gives the same result as the Weir formula at RQ = 1 (burning only carbohydrates ...
The respiratory quotient can be measured across a capillary bed of a particular organ or even a collection of cells in vitro. Most of the time RER and RQ are the same value, however, during a metabolic or respiratory acidosis/alkalosis RER and RQ do not have to be the same value. Valbaugh 11:45, 2 July 2009 (UTC)
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The partial pressure of carbon dioxide, along with the pH, can be used to differentiate between metabolic acidosis, metabolic alkalosis, respiratory acidosis, and respiratory alkalosis. Hypoventilation exists when the ratio of carbon dioxide production to alveolar ventilation increases above normal values – greater than 45mmHg.