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The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) supports the development and evaluation of new, revised, and alternative methods for chemical safety testing. Alternative methods are methods for safety testing of chemicals and chemical products that use fewer or no animals or that minimize or prevent ...
The EPAA focuses on selected priority areas. Typical examples include : Consistency approach for improved vaccine quality control; Acute toxicity testing; Support to the acceptance of the Extended One Generation Reproductive Toxicity Study (EOGRTS) New perspectives on safety, making use of computational chemistry, systems biology and stem cells
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) coordinates U.S. federal government evaluation of new, revised, and alternative test methods. Alternative methods are methods for safety testing of chemicals and chemical products that use fewer or no animals or that minimize or prevent animal pain and ...
A test method is a method for a test in science or engineering, such as a physical test, chemical test, or statistical test. It is a definitive procedure that produces a test result. [ 1 ] In order to ensure accurate and relevant test results, a test method should be "explicit, unambiguous, and experimentally feasible.", [ 2 ] as well as ...
Finnish Center for Alternative Methods (FICAM), since 2008 [115] FRANCOPA is the French platform dedicated to development, validation, and dissemination of alternative methods in animal testing. It was created on November 16, 2007. [116] The Italian Centro 3R was created in 2017. It is an interuniversity center dedicated to the promotion of the ...
Its goal was "to develop, validate, and promote laboratory methods and techniques that don't use animal test subjects". [1] It was the first centre in Canada dedicated to non-animal testing and the promotion of human-relevant alternatives. [2] [3] The CCAAM ceased operations on May 31, 2024 due to budget cuts at the University of Windsor. [4]
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Up-and-down procedure (or method) for toxicology tests in medicine is an alternative to the LD 50 test, in which animals are used for acute toxicity testing. [1] [2] It requires fewer animals to achieve similar accuracy as the LD 50 test because animals are dosed one at a time. [3]