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J&J has faced numerous civil lawsuits on behalf of children who were prescribed risperidone who grew breasts (a condition called gynecomastia); as of July 2016 there were about 1,500 cases in Pennsylvania state court in Philadelphia, and there had been a February 2015 verdict against J&J with $2.5 million awarded to a man from Alabama, a $1.75 ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
A survey of children with pervasive developmental disorder found that 16.5% were taking an antipsychotic drug, most commonly for irritability, aggression, and agitation. Both risperidone and aripiprazole have been approved by the US FDA for the treatment of irritability in autistic children and adolescents. [ 85 ]
Weight gain (causes less weight gain than clozapine, olanzapine and zotepine, around as much weight gain as quetiapine and more weight gain than amisulpride, aripiprazole, lurasidone, asenapine and ziprasidone) [5] (oral, adult, 8.7% to 20.9%; pediatric, 14% to 32.6% ; IM, adult, 8% to 10%)
[7] [8] There is evidence of clozapine, amisulpride, olanzapine, and risperidone being the most effective medications. However, a high proportion of studies of risperidone were undertaken by its manufacturer, Janssen-Cilag, and should be interpreted with this in mind. [9] In those on antipsychotics, continued use decreases the risk of relapse.
Tiapride is a drug that selectively blocks D 2 and D 3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. [2]
Drug regimen simplification: Adherence to medication therapy is inversely related to the frequency of dosing. [2] The antipsychotic quetiapine is typically dosed two to three times daily for the management of schizophrenia. [3] A simpler regimen would be a once daily administered antipsychotic. [1] For example, risperidone can be administered ...
The drug is sometimes described as a typical antipsychotic, [5] and sometimes described as an atypical antipsychotic. [6] Chemically, molindone is an indole and is structurally distinct from many other antipsychotics. [2] Molindone was first described by 1966 [7] and was introduced for medical use in 1974. [8] It remains marketed only in the ...