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  2. 2010 DePuy Hip Recall - Wikipedia

    en.wikipedia.org/wiki/2010_DePuy_Hip_Recall

    DePuy identified reasons for the failure of the hip replacement system as component loosening, component malalignment, infection, fracture of the bone, dislocation, metal sensitivity and pain. Additional complications from the hip replacement system may include increased metal ion levels in the blood, bone staining, necrosis, swelling, nerve ...

  3. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3] [5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [2]

  4. Metallosis - Wikipedia

    en.wikipedia.org/wiki/Metallosis

    In August 2010, DePuy recalled its hip replacement systems ASR XL Acetabular Hip Replacement System and ASR Hip Resurfacing System due to failure rates and side effects including metallosis. The recalls triggered a large number of lawsuits against DePuy and its parent company Johnson & Johnson upon claims that the companies knew about the ...

  5. Hip replacement - Wikipedia

    en.wikipedia.org/wiki/Hip_replacement

    Medical uses. Total hip replacement is most commonly used to treat joint failure caused by osteoarthritis.Other indications include rheumatoid arthritis, avascular necrosis, traumatic arthritis, protrusio acetabuli, certain hip fractures, benign and malignant bone tumors, arthritis associated with Paget's disease, ankylosing spondylitis and juvenile rheumatoid arthritis.

  6. Weight-loss drugs tied to benefit after hip replacement - AOL

    www.aol.com/news/weight-loss-drugs-tied-benefit...

    New diabetes and weight-loss drugs may benefit patients undergoing hip replacement, without adding to complication risks, according to preliminary data released on Monday at a large meeting of ...

  7. DePuy Synthes - Wikipedia

    en.wikipedia.org/wiki/DePuy_Synthes

    DePuy faces more than 11,000 plaintiffs nationwide over the ASR XL, which generally allege that the product is prone to degrading prematurely and shedding toxic metal debris, causing pain and necessitating revision surgeries that can be more invasive than the initial total hip replacements. In the first trial related to the product, a ...

  8. Supreme Court rejects multibillion-dollar Purdue Pharma ...

    www.aol.com/news/supreme-court-rejects...

    The Supreme Court on Thursday rejected a controversial settlement that would have sent billions of dollars to treatment programs and victims of the nation’s opioid epidemic but that also ...

  9. This Simple Trick Helped Me Avoid Hip Replacement - AOL

    www.aol.com/lifestyle/simple-trick-helped-avoid...

    Hip replacement seemed like my only option. I resisted the temptation because I understood that if I ran on a replaced hip, I would likely need a second hip replacement in my lifetime and I was ...