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The babies have a normal examination and attain normal developmental milestones. The MRI, interictal EEG (between seizures) and bloodwork is normal however genetic testing often shows a causal genetic variant (most commonly KCNQ2 or KCNQ3 in self-limited neonatal epilepsy, PRRT2 or less commonly SCN2A or SCN8A in self-limited infantile epilepsy ...
This form of epilepsy resolves after one or two years, and appears to be completely benign. The EEG of these children, between seizures, is normal. The brain appears normal on MRI scan. [4] [5] The familial and nonfamilial forms have overlapping features and the presence of a family history of infantile seizures may be the only distinguishing ...
Given the low to moderate sensitivity, a routine EEG (typically with a duration of 20–30 minutes) can be normal in people that have epilepsy. When an EEG shows interictal epileptiform discharges (e.g. sharp waves, spikes, spike-and-wave, etc.) it is confirmatory of epilepsy in nearly all cases (high specificity), however up to 3.5% of the ...
If it was an unprovoked seizure with abnormal brain imaging or abnormal EEG, then it is recommended to start anti-seizure medication. [3] If a person has an unprovoked seizure, but physical exam is normal, EEG is normal, and brain imaging is normal, then anti-seizure medication may not be needed. [ 3 ]
Treatment can be short and drugs can almost certainly be discontinued after two years without seizures and with normal EEG findings, perhaps even earlier. [4] Parental education about Rolandic epilepsy is the cornerstone of correct management. The traumatizing, sometimes long-lasting effect on parents is significant. [28]
In newly diagnosed epilepsy, magnetic resonance imaging (MRI) can detect brain lesion in up to 12 to 14% of persons with epilepsy. [31] However, for those with chronic epilepsy, MRI can detect brain lesion in 80% of the persons with epilepsy. [31] 3-Tesla MRI scan is advised for those with evidence of focal epilepsy such as temporal lobe ...
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