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Progression from TB infection to overt TB disease occurs when the bacilli overcome the immune system defenses and begin to multiply. In primary TB disease (some 1–5% of cases), this occurs soon after the initial infection. [13] However, in the majority of cases, a latent infection occurs with no obvious symptoms. [13]
The medical history includes obtaining the symptoms of pulmonary TB: productive, prolonged cough of three or more weeks, chest pain, and hemoptysis.Systemic symptoms include low grade remittent fever, chills, night sweats, appetite loss, weight loss, easy fatiguability, and production of sputum that starts out mucoid but changes to purulent. [1]
The symptoms of abdominal tuberculosis depends on the sites of involvement. The most common symptoms and signs of abdominal tuberculosis are abdominal pain, ascites and intestinal obstruction. Other clinical features are fever, altered bowel habits, loss of weight and a feeling of lump in the abdomen. [5]
Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. [1] [6] Historically, transmission of Mycobacterium bovis from dairy consumption was another frequent cause of tuberculous lymphadenitis, but incidence has drastically decreased in developed countries since the advent of pasteurization and other efforts to prevent bovine ...
TB is the world’s leading cause of death from a single infectious agent, with the World Health Organisation estimating that 10.8 million people were ill with the disease in 2023. Show comments ...
[2] [3] Cigarette smokers are 25% more likely to have lung damage, and more severe damage, after cure of a TB infection. [5] People who cook with 3-4 stoves instead of 1-2 stoves are more likely to have lung damage. A lack of heating also increased how often symptoms occurred. Alcoholism also increased the risk of PTLD. Ambient air pollution ...
Treatment of latent TB infection typically involves using a single drug for a prolonged period of time—the most common approach is Isoniazid for 9 months. Treatment of active TB disease is typically a combination of antibiotics, which results in patients being non-infectious to others usually within a few weeks.
In people who develop active TB of the lungs, also called pulmonary TB, the TB skin test will often be positive. In addition, they will show all the signs and symptoms of TB disease, and can pass the bacteria to others. So, if a person with TB of the lungs sneezes, coughs, talks, sings, or does anything that forces the bacteria into the air ...