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A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. [1] [2] This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC ...
Micrograph of a sessile serrated adenoma. H&E stain. Sessile serrated adenomas are characterized by (1) basal dilation of the crypts, (2) basal crypt serration, (3) crypts that run horizontal to the basement membrane (horizontal crypts), and (4) crypt branching. The most common of these features is basal dilation of the crypts.
The diagnosis of serrated polyposis syndrome is achieved when either one of two criteria are met: five or more serrated lesions/polyps proximal to the rectum (all ≥ 5 mm in size, with two lesions ≥10 mm), or >20 serrated lesions/polyps of any size distributed throughout the large bowel with five proximal to the rectum. [6]
A colorectal polyp is a polyp (fleshy growth) occurring on the lining of the colon or rectum. [1] Untreated colorectal polyps can develop into colorectal cancer. [2] Colorectal polyps are often classified by their behaviour (i.e. benign vs. malignant) or cause (e.g. as a consequence of inflammatory bowel disease).
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Sessile Serrated Adenoma, Transverse Colon, 0.4 cm. Pathological and histological images courtesy of Ed Uthman at flickr. Date: 16 June 2009, 11:12: Source: Sessile Serrated Adenoma, Transverse Colon, 0.4 cm. Uploaded by CFCF; Author: Ed Uthman from Houston, TX, USA
Traditional serrated adenoma is a premalignant type of polyp found in the colon, often in the distal colon (sigmoid, rectum). Traditional serrated adenomas are a type of serrated polyp, and may occur sporadically or as a part of serrated polyposis syndrome. Traditional serrated adenomas are relatively rare, accounting for less than 1% of all ...
In a universe where Earth and other countless planets have been conquered by the Jark Matter organization under the mysterious Don Armage, an insurgent force called "Rebellion" is established and gathers nine alien warriors from across the galaxy who are chosen by the Kyutama, magical stones with the power of the constellations, to become the Kyurangers; the humanoids Lucky, Stinger, Naga Ray ...