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A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron ...
Pages in category "Dopamine reuptake inhibitors" The following 99 pages are in this category, out of 99 total. This list may not reflect recent changes. ...
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS) and are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling.
At present, only one norepinephrine-dopamine reuptake inhibitor is approved by the FDA to treat depression: bupropion (Wellbutrin). It boosts the concentration of norepinephrine and dopamine ...
Chemical/generic names are listed first, with brand names in parentheses. All drugs listed are approved specifically for major depressive disorder unless noted otherwise. Selective serotonin reuptake inhibitors (SSRIs)
Bumetanide oral liquid (S-95008) – sodium–potassium–chloride symporter/cotransporter inhibitor and indirect GABAergic inhibitor [3] [4] Cariprazine (Reagila, Symvenu, Vraylar; MP-214, RGH-188, WID-RGC20) – dopamine D 2 and D 3 receptor partial agonist, serotonin 5-HT 1A receptor partial agonist, serotonin 5-HT 2B receptor antagonist ...
The skeletal structure of norepinephrine The skeletal structure of dopamine. A norepinephrine–dopamine reuptake inhibitor (NDRI) is a drug used for the treatment of clinical depression, attention deficit hyperactivity disorder (ADHD), narcolepsy, and the management of Parkinson's disease.
Lauflumide (flmodafinil, bisfluoromodafinil; NLS-14, NLS-4) – weak dopamine reuptake inhibitor, possibly other actions [80] Manifaxine (BW-1555U88, GW-320659) – norepinephrine–dopamine reuptake inhibitor [81] Mecamylamine (Inversine, Tridmac) – nicotinic acetylcholine receptor antagonist [82] MEM-68626 – 5-HT 6 receptor antagonist [83]