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The exact cause of morning sickness remains unknown. Nausea and vomiting in pregnancy is typically mild and self-limited, resolving on its own by the 14th week of pregnancy. Other causes should also be ruled out when considering treatment. Initial treatment is typically conservative, and may include changes to diet and emotional support.
Morning sickness, also called nausea and vomiting of pregnancy (NVP), is a symptom of pregnancy that involves nausea or vomiting. [1] Despite the name, nausea or vomiting can occur at any time during the day. [2] Typically the symptoms occur between the 4th and 16th weeks of pregnancy. [2]
Doxylamine is used in the combination drug pyridoxine/doxylamine to treat morning sickness (nausea and vomiting of pregnancy). [ 19 ] [ 20 ] [ 21 ] It is the only medication approved by the United States Food and Drug Administration for the treatment of morning sickness.
Antihistamines may be prescribed in early pregnancy for the treatment of nausea and vomiting along with symptoms of asthma and allergies. [54] First generation antihistamines include diphenhydramine (Benadryl), chlorpheniramine (Diabetic Tussin), hydroxyzine (Atarax), and doxepin (Sinequan). [55]
In cases of gastroenteritis, serotonin antagonists such as ondansetron were found to suppress nausea and vomiting, as well as reduce the need for IV fluid resuscitation. [22] The combination of pyridoxine and doxylamine is the first line treatment for pregnancy-related nausea and vomiting. [22]
Most often, nausea and vomiting symptoms during pregnancy resolve in the first trimester, however, some continue to experience symptoms. Hyperemesis gravidarum is diagnosed by the following criteria: greater than 3 vomiting episodes per day, ketonuria, and weight loss of more than 3 kg or 5% of body weight.
Of these side effects, more common ones include nausea, insomnia, tiredness and decreased libido. Often, they improve over several weeks as your body gets used to taking something new.
Hyperemesis gravidarum, which is a severe form of nausea and vomiting of pregnancy can lead to nutritional deficiencies, weight loss, electrolytes imbalance and is one of the leading causes of hospitalization in the first trimester of pregnancy. [36] Constipation is another GI symptom that is commonly encountered during pregnancy. It is ...
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