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Microangiopathy (also known as microvascular disease, small vessel disease (SVD) or microvascular dysfunction) is a disease of the microvessels, small blood vessels in the microcirculation. [1] It can be contrasted to macroangiopathies such as atherosclerosis , where large and medium-sized arteries (e.g., aorta , carotid and coronary arteries ...
These changes are most prominent in the kidney and can lead to ischemia and acute kidney failure. In the brain, a small cavity called a lacune is an ischemic cavity that can arise due to brain necrosis, due to arteriolosclerosis. [15] [16] Cause. It can be caused by chronic benign (essential) hypertension [17] malignant hypertension. [4] [18]
The risk factors include abdominal obesity, meaning excessive visceral fat tissue in and around the abdomen, atherogenic dyslipidemia which is a blood fat disorder, and elevated blood pressure. [7] Other risk factors are insulin resistance or intolerance to glucose, prothrombotic state or proinflammatory state.
Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). [1] This also refers to the condition of damage or rupture of small blood vessels. The best known and most prevalent angiopathy is diabetic angiopathy, a common complication of chronic diabetes.
Secondly, high blood pressure is a silent disease and thus it is vital for all diabetics to regularly check their blood pressure or have it checked at a doctor's office on a regular basis. The American Diabetes Association recommends that all diabetics get their blood pressure measured by a health care professional at least 2-5 times a year.
Buerger's disease – inflammation and swelling in small blood vessels, causing the vessels to narrow or become blocked by blood clots. [18] Raynaud syndrome – a peripheral vascular disorder that causes constriction of the peripheral blood vessels in the fingers and toes when a person is cold or experiencing stress. [19]
The original definition of cardiac syndrome X also mandated that ischemic changes on exercise (despite normal coronary arteries) were displayed, as shown on cardiac stress tests. [17] The primary cause of microvascular angina is unknown, but factors apparently involved are endothelial dysfunction and reduced flow (perhaps due to spasm) in the ...
Ischemic changes in the brain are irreversible, but the person with vascular dementia can demonstrate periods of stability or even mild improvement. [18] Since stroke is an essential part of vascular dementia, [ 13 ] the goal is to prevent new strokes.