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Piperacillin with tazobactam is administered through an intravenous (IV) method, where it is infused into the bloodstream over a period of 30 minutes to 4 hours so that the medication is delivered slowly and steadily.
Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when taken orally as the stomach will digest ...
Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt , tazobactam sodium.
Piperacillin-tazobactam is recommended as part of a three-drug regimen for the treatment of hospital-acquired pneumonia suspected as being due to infection by multi-drug resistant pathogens. [7] It is also one of several antibacterial drugs recommended for the treatment of infections known to be caused by anaerobic Gram-negative rods. [8]
Tazobactam, usually combined with piperacillin (Zosyn, Tazocin) Enmetazobactam, usually combined with cefepime ; β-lactamase inhibitors with a diazabicyclooctane core: Avibactam, approved in combination with ceftazidime (Avycaz, Zavicefta), currently undergoing clinical trials for combination with ceftaroline
Seizures are a dose-limiting toxicity for both imipenem and meropenem. [18] Clostridioides difficile-related diarrhea may occur in people treated with carbapenems or other broad-spectrum antibiotics. [19] Those with an allergy to penicillin may develop a cross sensitivity to carbapenems. [20]
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
A colored electron microscopy image of methicillin-resistant staphylococcus aureus (), a bacterium commonly targeted by broad-spectrum antibioticsA broad-spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, Gram-positive and Gram-negative, [1] or any antibiotic that acts against a wide range of disease-causing bacteria. [2]
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