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The size difference causes the difference in colors. Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. [ 1 ] The colloid is coloured usually either wine red (for spherical particles less than 100 nm) or blue-purple (for larger spherical particles or nanorods). [ 2 ]
Gold nanoparticles. Gold nanoparticles in chemotherapy and radiotherapy is the use of colloidal gold in therapeutic treatments, often for cancer or arthritis. Gold nanoparticle technology shows promise in the advancement of cancer treatments. Some of the properties that gold nanoparticles possess, such as small size, non-toxicity and non ...
A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter. [1][2] The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. [2]: 394 At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead.
Immunogold labeling or immunogold staining (IGS) is a staining technique used in electron microscopy. [2] This staining technique is an equivalent of the indirect immunofluorescence technique for visible light. Colloidal gold particles are most often attached to secondary antibodies which are in turn attached to primary antibodies designed to ...
Nanomedicine is the medical application of nanotechnology. [ 1 ] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the ...
Nanoparticle delivery through the BBB can be increased by introducing peptide conjugates to improve permeability to the central nervous system. For instance, recent studies have shown an improvement in gold nanoparticle delivery efficiency by conjugating a peptide that binds to the transferrin receptors expressed in brain endothelial cells. [12]
Gold nanoparticles can be purchased or synthesized via a variety of methods. [12] Several strategies exist for functionalizing gold nanoparticles with single-stranded DNA; one of the most commonly utilized strategies involves introducing thiol-terminated DNA to a solution of gold nanoparticles and gradually increasing the concentration of a salt, like NaCl.
Silica nanoparticles induce coagulation through contact activation of coagulation factor XII (Hageman factor). [2] The silica particles are desiccants, which adsorb and hold water vapor. [ 3 ] This is used in the tubes so the blood adheres to the surface of the tiny silica particles and begins to clot.