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Meloxicam has been shown, especially at low therapeutic doses, to selectively inhibit COX-2 over COX-1. [7] Meloxicam concentrations in synovial fluid range from 40% to 50% of those in plasma. The free fraction in synovial fluid is 2.5 times higher than in plasma, due to the lower albumin content in synovial fluid as compared to plasma.
Bursitis is the inflammation of one or more bursae (synovial sacs) of synovial fluid in the body. They are lined with a synovial membrane that secretes a lubricating synovial fluid. [1] There are more than 150 bursae in the human body. [1] The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone.
Prepatellar bursitis. Prepatellar bursitis is an inflammation of the prepatellar bursa at the front of the knee. It is marked by swelling at the knee, which can be tender to the touch and which generally does not restrict the knee's range of motion. It can be extremely painful and disabling as long as the underlying condition persists.
Olecranon bursitis. Relatively common. [2] Olecranon bursitis is a condition characterized by swelling, redness, and pain at the tip of the elbow. [1][2] If the underlying cause is due to an infection, fever may be present. [2] The condition is relatively common and is one of the most frequent types of bursitis. [2]
Greater trochanteric pain syndrome. Greater trochanteric pain syndrome (GTPS), a form of bursitis, is inflammation of the trochanteric bursa, a part of the hip. This bursa is at the top, outer side of the femur, between the insertion of the gluteus medius and gluteus minimus muscles into the greater trochanter of the femur and the femoral shaft.
Subacromial bursitis. Subacromial bursitis is a condition caused by inflammation of the bursa that separates the superior surface of the supraspinatus tendon (one of the four tendons of the rotator cuff) from the overlying coraco-acromial ligament, acromion, and coracoid (the acromial arch) and from the deep surface of the deltoid muscle. [1]
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