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An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.It secretes hormones that influence stages of the menstrual cycle.In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty, [1] [2] each with the potential to release an egg cell (ovum) at ovulation for fertilization. [3]
In biology, folliculogenesis is the maturation of the ovarian follicle, ... Diagram of folliculogenesis, starting from pre-antral (late secondary), courtesy NCBI.
The outer layer is the ovarian cortex, consisting of ovarian follicles and stroma in between them. Included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte. Theca of follicle, antrum and liquor folliculi are also contained in the follicle.
Follicular phase diagram of hormones and their origins Follicle-stimulating hormone (FSH) is secreted by the anterior pituitary gland (Figure 2). FSH secretion begins to rise in the last few days of the previous menstrual cycle, [ 3 ] and is the highest and most important during the first week of the follicular phase [ 4 ] (Figure 1).
The ovarian follicles rupture and release the secondary oocyte ovarian cells. [1] After ovulation, during the luteal phase, the egg will be available to be fertilized by sperm. If it is not, it will break down in less than a day. Meanwhile, the uterine lining (endometrium) continues to thicken to be able to receive a fertilized egg.
Menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the ...
Ovarian culture is an in-vitro process that allows for the investigation of the development, toxicology and pathology of the ovary. [1] This technique can also be used to study possible applications of fertility treatments e.g. isolating oocytes from primordial ovarian follicles that could be used for fertilisation.
Section of vesicular ovarian follicle of a cat. X 50. Membrana granulosa labeled at upper left. In the development of the urinary and reproductive organs, the oogonia become invaginated in the gonadal ridge. The embryological origin of granulosa cells remains controversial.