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A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]
Origin System(s) Notes Alice The Last of Us Part II: PlayStation 4: One of many dogs trained by the WLF to assist in patrolling Seattle, Alice is primarily handled by supporting character Mel. Amaterasu: Ōkami: PlayStation 2: The main character of the game, Amaterasu is the Japanese Shinto sun goddess, who has inhabited the form of a white ...
Omeprazole was a subject of a patent litigation in the U.S. [66] The invention involved application of two different coatings to a drug in pill form to ensure that the omeprazole did not disintegrate before reaching its intended site of action in stomach. Although the solution by means of two coating was obvious, the patent was found valid ...
Down Load was met with generally favorable reviews. [4] [6] [7] [9] [11] The Japanese publication Micom BASIC Magazine ranked the game sixteenth in popularity in its November 1990 issue, and it received a score of 21.88 out of 30 in a 1993 readers' poll conducted by PC Engine Fan, ranking among PC Engine titles at the number 175 spot.
Shadow Dancer (1989 video game) Shadow Dancer: The Secret of Shinobi; Sheep (video game) Sheep, Dog 'n' Wolf; Sleepwalker (video game) Snoopy and the Red Baron (video game) Snoopy Concert; Snoopy Flying Ace; Snoopy Tennis; Snoopy vs. the Red Baron (video game) Snoopy's Magic Show; Snoopy's Silly Sports Spectacular; Solatorobo: Red the Hunter ...
For games that were originally released as freeware, see List of freeware video games. For free and open-source games, and proprietary games re-released as FLOSS, see List of open-source video games. For proprietary games with released source code (and proprietary or freeware content), see List of commercial video games with available source code.
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Some games feature animals with realistic appearances but unrealistic behavior. A lot of them feature dogs or cats as the main character, but other animals get starring roles as well. These animals include deer, wolves, sharks, and foxes. Examples of this type of animal game include Goat Simulator and Catlateral Damage. [9]