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Polyploidy occurs in some tissues of animals that are otherwise diploid, such as human muscle tissues. [45] This is known as endopolyploidy. Species whose cells do not have nuclei, that is, prokaryotes, may be polyploid, as seen in the large bacterium Epulopiscium fishelsoni. [46] Hence ploidy is defined with respect to a cell.
WI-38 was invaluable to early researchers, especially those studying virology and immunology, since it was a readily available cell line of normal human tissue. Unlike the HeLa cell line, which were cancerous cells, WI-38 was a normal human cell population. Researchers in labs across the globe have since used WI-38 in their discoveries, most ...
Human diploid cells have 46 chromosomes (the somatic number, 2n) and human haploid gametes (egg and sperm) have 23 chromosomes (n). Retroviruses that contain two copies of their RNA genome in each viral particle are also said to be diploid. Examples include human foamy virus, human T-lymphotropic virus, and HIV. [29]
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living organisms.This number, along with the visual appearance of the chromosome, is known as the karyotype, [1] [2] [3] and can be found by looking at the chromosomes through a microscope.
Most human cells are diploid so they contain twice as much DNA (~6.2 billion base pairs). In 2023, a draft human pangenome reference was published. [8] It is based on 47 genomes from persons of varied ethnicity. [8] Plans are underway for an improved reference capturing still more biodiversity from a still wider sample. [8]
In the diplontic life cycle (with pre-gametic meiosis), as in humans, the organism is multicellular and diploid, grown by mitosis from a diploid cell called the zygote. The organism's diploid germ-line stem cells undergo meiosis to make haploid gametes (the spermatozoa in males and ova in females), which fertilize to form the zygote.
Animals have life cycles with a single diploid multicellular phase that produces haploid gametes directly by meiosis. Male gametes are called sperm, and female gametes are called eggs or ova. In animals, fertilization of the ovum by a sperm results in the formation of a diploid zygote that develops by repeated mitotic divisions into a diploid ...
The members of an autosome pair in a diploid cell have the same morphology, unlike those in allosomal (sex chromosome) pairs, which may have different structures. The DNA in autosomes is collectively known as atDNA or auDNA. [2] For example, humans have a diploid genome that usually contains 22 pairs of autosomes and one allosome pair (46 ...