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The source of interferon-gamma can be CD4 + T cells, CD8 + T cells, natural killer cells, B cells, natural killer T cells, monocytes, other macrophages, or dendritic cells. [38] Nitric oxide is then released from the macrophage and, because of its toxicity, kills microbes near the macrophage. [14]
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system.They are a kind of large granular lymphocytes [1] [2] (LGL), and belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. [3]
The innate leukocytes include: natural killer cells, mast cells, eosinophils, basophils; and the phagocytic cells include macrophages, neutrophils, and dendritic cells, and function within the immune system by identifying and eliminating pathogens that might cause infection.
Rather, cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, ... (ILC1 and Natural killer cells) CD4 + T H 1 Cells.
The other cells involved in the innate response include innate lymphoid cells, mast cells, eosinophils, basophils, and natural killer cells. [ 28 ] Phagocytosis is an important feature of cellular innate immunity performed by cells called phagocytes that engulf pathogens or particles.
Fc receptors are found on a number of cells in the immune system including phagocytes like macrophages and monocytes, granulocytes like neutrophils and eosinophils, and lymphocytes of the innate immune system (natural killer cells) or adaptive immune system (e.g., B cells).
Macrophages are professional phagocytes and are highly specialized in removal of dying or dead cells and ... dendritic cells, natural killer cells, basophils, ...
Their key effector cytokine is IL-10. Their main effector cells are NK cells as well as CD8 T cells, IgG B cells, and IL-10 CD4 T cells. The key THαβ transcription factors are STAT1 and STAT3 as well as IRFs. IL-10 from CD4 T cells activate NK cells' ADCC to apoptose virus-infected cells and to induce host as well as viral DNA fragmentation ...