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  2. Acanthosis nigricans - Wikipedia

    en.wikipedia.org/wiki/Acanthosis_nigricans

    Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] ... as seen in diabetes mellitus.

  3. Rabson–Mendenhall syndrome - Wikipedia

    en.wikipedia.org/wiki/Rabson–Mendenhall_syndrome

    A skin abnormality known as acanthosis nigricans, which involves a discoloration (hyperpigmentation) and "velvety" thickening (hyperkeratosis) of the skin around skin fold regions of the neck, groin and under arms is also a common symptom. [1] Symptoms will negatively impact the daily life of the patient, and will persist until treated.

  4. Glossary of diabetes - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_diabetes

    Acanthosis nigricans A brown to black, ... Diabetes is a systemic disease because it involves many parts of the body such as the pancreas, eyes, kidneys, heart, and ...

  5. HAIR-AN syndrome - Wikipedia

    en.wikipedia.org/wiki/HAIR-AN_syndrome

    Patients with both underlying mechanisms of insulin resistance may have more severe hyperandrogenism. Insulin resistance is also associated with diabetes, heart disease and excessive darkening of the skin (acanthosis nigricans) [6]

  6. Acanthosis nigricans-muscle cramps-acral enlargement syndrome

    en.wikipedia.org/wiki/Acanthosis_nigricans...

    Acanthosis nigricans-muscle cramps-acral enlargement syndrome, also known as Acanthosis nigricans-insulin resistance-muscle cramps-acral enlargement syndrome is an extremely rare genetic disorder which is characterized by the appearance of acanthosis nigricans, insulin resistance, muscle cramps of severe intensity, and acral hypertrophy ...

  7. Alström syndrome - Wikipedia

    en.wikipedia.org/wiki/Alström_syndrome

    Symptoms include early-onset type 2 diabetes, cone-rod dystrophy resulting in blindness, sensorineural hearing loss and dilated cardiomyopathy. Endocrine disorders typically also occur, such as hypergonadotrophic hypogonadism and hypothyroidism, as well as acanthosis nigricans resulting from hyperinsulinemia. Developmental delay is seen in ...

  8. Crouzonodermoskeletal syndrome - Wikipedia

    en.wikipedia.org/wiki/Crouzonodermoskeletal_syndrome

    Crouzonodermoskeletal syndrome is a disorder characterized by the premature joining of certain bones of the skull (craniosynostosis) during development and a skin condition called acanthosis nigricans. [1] Some of the signs and symptoms of Crouzonodermoskeletal syndrome are similar to those seen with Crouzon syndrome.

  9. Insulin receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin_receptor

    For this reason "insulin insensitivity", or a decrease in insulin receptor signaling, leads to diabetes mellitus type 2 – the cells are unable to take up glucose, and the result is hyperglycemia (an increase in circulating glucose), and all the sequelae that result from diabetes. Patients with insulin resistance may display acanthosis nigricans.

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