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Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump .
Eli Lilly and Company developed and marketed the first rapid-acting insulin analogue (insulin lispro rDNA) Humalog. It was engineered through recombinant DNA technology so that the penultimate lysine and proline residues on the C-terminal end of the B-chain were reversed.
Insulin Lispro Injection was also priced 50% lower than the list price of Humalog U-100. Lilly said that since then 10% of people using Humalog have transitioned to the cheaper injection.
The shortage applies to the company's 10 mL vials of Humalog and Insulin Lispro Injection medications.
1982 Genentech synthetic human insulin (above) approved; 1983 Eli Lilly and Company produces biosynthetic human insulin with recombinant DNA technology, Humulin; 1985 Axel Ullrich sequences a human cell membrane insulin receptor. 1988 Novo Nordisk produces recombinant biosynthetic human insulin; 1996 Lilly Humalog "lispro" insulin analogue ...
Insulin, which can retail for hundreds and hundreds of dollars out-of-pocket, just got much more affordable. Wednesday, via virtual press The post Eli Lilly is cutting insulin prices by 70 percent ...
Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify
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