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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
In 2002, an expert panel made recommendations about the evaluation and treatment of probable nursing home-acquired pneumonia. [22] They defined probably pneumonia, emphasized expedite antibiotic treatment (which is known to improve survival) and drafted criteria for the hospitalization of willing patients.
Anaerobic bacteria can also be isolated in about 35% of individuals who have nosocomial-acquired aspiration pneumonia [25] and pneumonia associated with tracheostomy with and without mechanical ventilation, [26] where they are often isolated along with Enterobacteriaceae, Pseudomonas spp. and Staphylococcus aureus. It is important that ...
Additional consideration is given to the treatment setting; most patients are cured by oral medication, while others must be hospitalized for intravenous therapy or intensive care. Current treatment guidelines recommend a beta-lactam, like amoxicillin, and a macrolide, like azithromycin or clarithromycin, or a quinolone, such as levofloxacin.
Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is contraindicated: Produces toxic free radicals that disrupt DNA and proteins. This non-specific mechanism is responsible for its activity against a variety of bacteria ...
A few antibiotics have received marketing authorization in the last seven years. The cephalosporin ceftaroline and the lipoglycopeptides oritavancin and telavancin have been approved for the treatment of acute bacterial skin and skin structure infection and community-acquired bacterial pneumonia. [162]
Tetracycline, metronidazole and bismuth salt combination [33] (No vaccine or preventive drug) [33] Klebsiella pneumoniae: Mouth, skin, and gut flora. [64] Pneumonia upon aspiration; Klebsiella pneumonia, with significant lung necrosis and hemoptysis [48] Hospital-acquired urinary tract infection and sepsis [48] 3rd generation cephalosporin [48 ...