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Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
[1] [3] [4] [5] In the thyrotoxic phase, the follicular cells of the thyroid gland are damaged leading to release of pre-formed thyroid hormone and symptoms of thyrotoxicosis. The damage to the follicles impairs ability to produce and secrete thyroid hormones which then leads to a hypothyroid phase.
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
[3] [4] Other symptoms, such as dysphagia and breathing difficulties caused by airway blockage, are uncommon. [2] The thyroid gland is extremely painful, rigid, and swollen, which can be symmetrical or asymmetrical. [2] Approximately half of affected adolescents and two-thirds of adults have widespread thyroid gland involvement.
Several reasons have been identified as to why prescriptions changed from desiccated thyroid treatment. Although thyroid extract was useful and usually effective, some patients continued to complain of fatigue, weight gain, or other symptoms. Dosing until the 1960s was often a matter of prolonged adjustment trials. [19]
Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...
The first sign of Ord's thyroiditis is the atrophy of the thyroid gland from the start this can be identified by ultrasound. [2] Another sign to help identify this disease is the presence of blocking anti-TSH receptors. Ord's thyroiditis can share symptoms with functional hypothyroidism. [3]
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