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In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]
Sights that use dot reticles are almost invariably measured in minutes of arc, sometimes called "minutes of angle" or "moa". Moa is a convenient measure for shooters using Imperial or US customary units , since 1 moa subtends approximately 1 in (25 mm) at a distance of 100 yd (91 m), which makes moa a convenient unit to use in ballistics ...
As a result, the use by medical practitioners of these older MAOIs declined. When scientists discovered that there are two different MAO enzymes (MAO-A and MAO-B), they developed selective compounds for MAO-B, (for example, selegiline , which is used for Parkinson's disease), to reduce the side-effects and serious interactions.
An alternative variant uses perpendicular hash lines instead of dots, and is known as the mil-hash reticle. Such graduated reticles, along with those with MOA-based increments, are collectively and unofficially called "milling reticles", and have gained significant acceptance in NATO and other military and law enforcement organizations.
Reticle of Bell & Howell Pocket Comparator Reticle accessory (PD-8) used in sniper rifles A reticle , or reticule [ 1 ] [ 2 ] also known as a graticule , is a pattern of fine lines or markings built into the eyepiece of an optical device such as a telescopic sight , spotting scope , theodolite , optical microscope or the screen of an ...
4128 17161 Ensembl ENSG00000189221 ENSMUSG00000025037 UniProt P21397 Q64133 RefSeq (mRNA) NM_001270458 NM_000240 NM_173740 RefSeq (protein) NP_000231 NP_001257387 NP_776101 Location (UCSC) Chr X: 43.65 – 43.75 Mb Chr X: 16.49 – 16.55 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MAOA gene is located on the short (p) arm of the X chromosome at position 11.3. Monoamine oxidase A ...
Pronunciation follows convention outside the medical field, in which acronyms are generally pronounced as if they were a word (JAMA, SIDS), initialisms are generally pronounced as individual letters (DNA, SSRI), and abbreviations generally use the expansion (soln. = "solution", sup. = "superior").
A milliradian (SI-symbol mrad, sometimes also abbreviated mil) is an SI derived unit for angular measurement which is defined as a thousandth of a radian (0.001 radian). ). Milliradians are used in adjustment of firearm sights by adjusting the angle of the sight compared to the barrel (up, down, left, or