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Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever [1] [2] [9] is a disease caused by parasitic flatworms called schistosomes. [5] It affects the urinary tract or the intestines. [5] Symptoms include abdominal pain, diarrhea, bloody stool, or blood in the urine. [5]
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Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans. It is classified as a neglected tropical disease. As of 2021, the World Health Organization reports that 251.4 million people have schistosomiasis and most of it is due to S. mansoni. [1]
Symptoms of all forms of schistosomiasis are caused by the immune system's reaction to the eggs, rather than the adult worms themselves. [5] A few hours to days after cercariae invade the skin, some people experience pruritus and raised papules at the site of penetration. This is called cercarial dermatitis, also known as swimmer's itch.
These symptoms negatively impact nutritional status, including decreased absorption of micronutrients, loss of appetite, weight loss, and intestinal blood loss that can often result in anemia. It may also cause physical and mental disabilities, delayed growth in children, and skin irritation around the anus and vulva.
Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including nine carnivores, 16 rodents, one primate (human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.
Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis [15]
It is found in Africa and the Middle East. It is the major agent of schistosomiasis, the most prevalent parasitic infection in humans. [1] It is the only blood fluke that infects the urinary tract, causing urinary schistosomiasis, and is a leading cause of bladder cancer (only next to tobacco smoking). [2] [3] The diseases are caused by the eggs.