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  2. Machine learning in bioinformatics - Wikipedia

    en.wikipedia.org/wiki/Machine_learning_in...

    Hierarchical algorithms find successive clusters using previously established clusters, whereas partitional algorithms determine all clusters at once. Hierarchical algorithms can be agglomerative (bottom-up) or divisive (top-down). Agglomerative algorithms begin with each element as a separate cluster and merge them in successively larger clusters.

  3. Substitution model - Wikipedia

    en.wikipedia.org/wiki/Substitution_model

    In biology, a substitution model, also called models of sequence evolution, are Markov models that describe changes over evolutionary time. These models describe evolutionary changes in macromolecules, such as DNA sequences or protein sequences, that can be represented as sequence of symbols (e.g., A, C, G, and T in the case of DNA or the 20 "standard" proteinogenic amino acids in the case of ...

  4. Algorithm - Wikipedia

    en.wikipedia.org/wiki/Algorithm

    Flowchart of using successive subtractions to find the greatest common divisor of number r and s. In mathematics and computer science, an algorithm (/ ˈ æ l ɡ ə r ɪ ð əm / ⓘ) is a finite sequence of mathematically rigorous instructions, typically used to solve a class of specific problems or to perform a computation. [1]

  5. Evolutionary game theory - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_game_theory

    In biology, strategies are genetically inherited traits that control an individual's action, analogous with computer programs. The success of a strategy is determined by how good the strategy is in the presence of competing strategies (including itself), and of the frequency with which those strategies are used. [ 9 ]

  6. Evolutionary algorithm - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_algorithm

    Differential evolution – Based on vector differences and is therefore primarily suited for numerical optimization problems. Coevolutionary algorithm – Similar to genetic algorithms and evolution strategies, but the created solutions are compared on the basis of their outcomes from interactions with other solutions.

  7. Crossover (evolutionary algorithm) - Wikipedia

    en.wikipedia.org/wiki/Crossover_(evolutionary...

    Different algorithms in evolutionary computation may use different data structures to store genetic information, and each genetic representation can be recombined with different crossover operators. Typical data structures that can be recombined with crossover are bit arrays , vectors of real numbers, or trees .

  8. Distance matrices in phylogeny - Wikipedia

    en.wikipedia.org/wiki/Distance_matrices_in_phylogeny

    These regression formulae minimize the residual differences between path-distances along the tree and pairwise distances in the data matrix, effectively "fitting" the tree to the empirical distances. In contrast, ME accepts the tree with the shortest sum of branch lengths, and thus minimizes the total amount of evolution assumed.

  9. Similarity measure - Wikipedia

    en.wikipedia.org/wiki/Similarity_measure

    The Jaccard index formula measures the similarity between two sets based on the number of items that are present in both sets relative to the total number of items. It is commonly used in recommendation systems and social media analysis [ citation needed ] .