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Cocaine stimulates the mesolimbic pathway in the brain. [15] Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. [12] Physical effects may include a fast heart rate, sweating, and dilated pupils. [12] High doses can result in high blood pressure or high body temperature. [16]
Toggle Physical and chemical properties subsection. 1.1 Synthesis. 2 Recreational use. ... Crack cocaine, commonly known simply as crack, and also known as rock, ...
It is a primary metabolite of cocaine, [1] and is pharmacologically inactive. [2] It is the corresponding carboxylic acid of cocaine, its methyl ester. It is formed in the liver by the metabolism of cocaine by hydrolysis, catalysed by carboxylesterases, and subsequently excreted in the urine. It is readily synthesised by boiling cocaine ...
This page provides supplementary chemical data on Cocaine in free base form. More commonly available "powder cocaine" is a hydrochloride salt whose properties will differ. Material Safety Data Sheet
Phenacetin has been used as a cutting agent to adulterate cocaine in the UK and Canada, due to the similar physical properties. [10] There, it has been given the nickname "magic". Due to its low cost, phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research. [why ...
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the world, and it is a serious crime in specific contexts ...
Coca leaf is the raw material for the manufacture of the drug cocaine, a powerful stimulant and anaesthetic extracted chemically from large quantities of coca leaves. Today, since it has mostly been replaced as a medical anaesthetic by synthetic analogues such as procaine, cocaine is best known as an illegal recreational drug.
Cocaine is a commonly used stimulant. Stimulants, also known as "psychostimulants", [94] induce euphoria with improvements in mental and physical function, such as enhanced alertness, wakefulness, and locomotion. Stimulants are also occasionally called "uppers".