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Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia , acne , chlamydia infections , Lyme disease , cholera , typhus , and syphilis . [ 1 ]
The antibiotics most frequently used to treat acne vulgaris are erythromycin, clindamycin, doxycycline, and minocycline. [ 40 ] [ 41 ] [ 42 ] Several other families of antibiotics are also active against C. acnes bacteria, including quinolones, cephalosporins, pleuromutilins, penicillins, and sulfonamides.
Treatment of Clostridioides (formerly Clostridium) difficile infection. [8] May be more narrow-spectrum than vancomycin, resulting in less bowel microbiota alteration. [9] Nausea (11%), vomiting, and abdominal pain. [10] Bactericidal in susceptible organisms such as C. difficile by inhibiting RNA polymerase, thereby inhibiting protein synthesis ...
The drug isn’t generally used as a so-called first-line treatment for acne. It’s considered an option for women if other medications, including creams or oral antibiotics, don’t work.
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The use of doxycycline in acne vulgaris has been associated with increased risk of Crohn's disease, [9] although a later study indicated a link between acne vulgaris and IBS irrespective of the use of antibiotics. [10] Likewise, the use of minocycline in acne vulgaris has been associated with skin and gut dysbiosis. [11]
One or both ingredients may be antibiotics. [1] Antibiotic combinations are increasingly important because of antimicrobial resistance. [2] This means that individual antibiotics that used to be effective are no longer effective, [1] and because of the absence of new classes of antibiotic, they allow old antibiotics to be continue to be used. [2]
(formerly known as TP-434) received FDA approval on August 27, 2018, for treatment of complicated intra-abdominal infections. [54] Sarecycline: 16+ hours (long) (formerly known as WC 3035) received FDA approval on October 1, 2018, for treatment of moderate to severe acne vulgaris. [55] Sarecycline is a narrow-spectrum antibiotic. [56] [57 ...